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Overview
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Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers
sgRNA lentiviral particle information
• Functional titer: 1x10^8 TU/ml
• Titration method: counting puromycin resistant cell clones
• Purity: In vivo grade
• Pseudotype: VSVG
• Storage buffer: LentiShield™ lentivirus storage buffer
• Storage: condition -80°C
• Availability: 3-5 weeks
sgRNA lentiviral plasmid information
• Promoter for target sgRNA: U6
• Mammalian selection: puromycin
• Promoter for mammalian selection gene: EF1a
• E.coli selection: Amp
• Storage condition: -20°C
• Availability: 1-2 weeksPlease contact us at for specific academic pricing.
Target Information
Target NameHuman CSGALNACT1About TargetGene symbol: CSGALNACT1
Synonyms: beta4GalNAcT ChGn ChGn-1 CSGalNAcT-1
Species: HUMAN
Gene ID: 55790
Summary: This gene encodes an enzyme that transfers N-acetylglucosamine (GalNAc) to the core tetrasaccharide linker and to elongating chondroitin sulfate chains in proteoglycans. Knockout of the orthologous mouse gene indicates that the protein is necessary for normal cartilage development and aggrecan metabolism. Mutations in this gene are associated with multiple sclerosis progression, and with mild skeletal dysplasia and joint laxity. [provided by RefSeq, Aug 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001130518:4:1 NM_001354475:4:1 NM_001354476:3:1 NM_001354477:4:1 NM_001354480:5:1 NM_001354481:4:1 NM_001354483:3:1 NM_001354484:4:1 NM_001354485:4:1 NM_001354487:4:1 NM_001354488:4:1 NM_001354489:4:1 NM_001354490:3:1 NM_001354491:5:1 NM_001354492:3:1 NM_001354494:4:1 NM_001354495:4:1 NM_001354496:4:1 NM_001354497:2:1 NM_001354498:4:1 NM_001354499:4:1 NM_018371:4:1
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- Properties
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Overview