Lentiviral human CSGALNACT1 sgRNA gene knockout kit

Lentiviral human CSGALNACT1 sgRNA gene knockout kit

Catalog Number:
CGKK545244FEN
Mfr. No.:
HKO-612066
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human CSGALNACT1
          About Target
          Gene symbol: CSGALNACT1
          Synonyms: beta4GalNAcT ChGn ChGn-1 CSGalNAcT-1
          Species: HUMAN
          Gene ID: 55790
          Summary: This gene encodes an enzyme that transfers N-acetylglucosamine (GalNAc) to the core tetrasaccharide linker and to elongating chondroitin sulfate chains in proteoglycans. Knockout of the orthologous mouse gene indicates that the protein is necessary for normal cartilage development and aggrecan metabolism. Mutations in this gene are associated with multiple sclerosis progression, and with mild skeletal dysplasia and joint laxity. [provided by RefSeq, Aug 2017].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001130518:4:1 NM_001354475:4:1 NM_001354476:3:1 NM_001354477:4:1 NM_001354480:5:1 NM_001354481:4:1 NM_001354483:3:1 NM_001354484:4:1 NM_001354485:4:1 NM_001354487:4:1 NM_001354488:4:1 NM_001354489:4:1 NM_001354490:3:1 NM_001354491:5:1 NM_001354492:3:1 NM_001354494:4:1 NM_001354495:4:1 NM_001354496:4:1 NM_001354497:2:1 NM_001354498:4:1 NM_001354499:4:1 NM_018371:4:1
      • Properties
        • * For Research Use Only.

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