Lentiviral human CRYM sgRNA gene knockout kit

Human CRYM

Gene symbol: CRYM
Synonyms: DFNA40 THBP
Species: HUMAN
Gene ID: 1428
Summary: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001888:3:1 NM_001376256:1:1