Lentiviral human CREB3 sgRNA gene knockout kit

Human CREB3

Gene symbol: CREB3
Synonyms: LUMAN LZIP sLZIP
Species: HUMAN
Gene ID: 10488
Summary: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_006368:2:2