Lentiviral human COL7A1 sgRNA gene knockout kit

Human COL7A1

Gene symbol: COL7A1
Synonyms: EBD1 EBDCT EBR1 NDNC8
Species: HUMAN
Gene ID: 1294
Summary: This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000094:3:3