Lentiviral human COL4A6 sgRNA gene knockout kit

Human COL4A6

Gene symbol: COL4A6
Synonyms: CXDELq22.3 DELXq22.3 DFNX6
Species: HUMAN
Gene ID: 1288
Summary: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_033641:21:21 NM_001847:21:21 NM_001287758:21:21 NM_001287759:21:21 NM_001287760:21:21