Lentiviral human CNOT7 sgRNA gene knockout kit

Human CNOT7

Gene symbol: CNOT7
Synonyms: CAF-1 CAF1 Caf1a hCAF-1
Species: HUMAN
Gene ID: 29883
Summary: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_013354:4:3 NM_054026:4:3 NM_001322087:5:3 NM_001322088:4:3 NM_001322089:4:3 NM_001322090:5:3 NM_001322091:4:3 NM_001322092:5:3 NM_001322093:5:4 NM_001322094:4:3 NM_001322095:5:2 NM_001322096:5:2 NM_001322097:5:2 NM_001322098:5:2 NM_001322099:5:2 NM_001322100:6:2