Lentiviral human CHFR sgRNA gene knockout kit

Human CHFR

Gene symbol: CHFR
Synonyms: RNF116 RNF196
Species: HUMAN
Gene ID: 55743
Summary: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001161344:7:6 NM_001161345:7:6 NM_001161346:7:6 NM_001161347:5:4 NM_018223:7:6