Lentiviral human CHD8 sgRNA gene knockout kit

Human CHD8

Gene symbol: CHD8
Synonyms: AUTS18 HELSNF1
Species: HUMAN
Gene ID: 57680
Summary: This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001170629:3:2 NM_020920:3:2