Lentiviral human CES1 sgRNA gene knockout kit

Human CES1

Gene symbol: CES1
Synonyms: ACAT CE-1 CEH CES2 hCE-1 HMSE HMSE1 PCE-1 REH SES1 TGH
Species: HUMAN
Gene ID: 1066
Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001025195:3:3 NM_001025194:3:3 NM_001266:3:3