Lentiviral human CERKL sgRNA gene knockout kit

Human CERKL

Gene symbol: CERKL
Synonyms: RP26
Species: HUMAN
Gene ID: 375298
Summary: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_201548:1:1 NM_001030311:1:1 NM_001030312:1:1 NM_001030313:1:1 NM_001160277:1:1