Lentiviral human CD82 sgRNA gene knockout kit

Human CD82

Gene symbol: CD82
Synonyms: 4F9 C33 GR15 IA4 KAI1 R2 SAR2 ST6 TSPAN27
Species: HUMAN
Gene ID: 3732
Summary: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_002231:5:3 NM_001024844:5:3