Lentiviral human CCT5 sgRNA gene knockout kit

Human CCT5

Gene symbol: CCT5
Synonyms: CCT-epsilon CCTE HEL-S-69 PNAS-102 TCP-1-epsilon
Species: HUMAN
Gene ID: 22948
Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_012073:5:5