Lentiviral human CBX1 sgRNA gene knockout kit

Human CBX1

Gene symbol: CBX1
Synonyms: CBX HP1-BETA HP1Hs-beta HP1Hsbeta M31 MOD1 p25beta
Species: HUMAN
Gene ID: 10951
Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_006807:3:2 NM_001127228:3:2