Lentiviral human CAMK2A sgRNA gene knockout kit

Human CAMK2A

Gene symbol: CAMK2A
Synonyms: CAMKA CaMKIIalpha CaMKIINalpha MRD53 MRT63
Species: HUMAN
Gene ID: 815
Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_015981:10:10 NM_171825:10:10 NM_001363989:11:10 NM_001363990:11:10 NM_001369025:10:10