Lentiviral human BSCL2 sgRNA gene knockout kit

Human BSCL2

Gene symbol: BSCL2
Synonyms: GNG3LG HMN5 PELD SPG17
Species: HUMAN
Gene ID: 26580
Summary: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001122955:4:4 NM_032667:4:3 NM_001130702:4:3