Lentiviral human BPGM sgRNA gene knockout kit

Human BPGM

Gene symbol: BPGM
Synonyms: DPGM ECYT8
Species: HUMAN
Gene ID: 669
Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001724:2:1 NM_001293085:3:1 NM_199186:3:1