Lentiviral human BCAS1 sgRNA gene knockout kit

Lentiviral human BCAS1 sgRNA gene knockout kit

Catalog Number:
CGKK546453FEN
Mfr. No.:
HKO-610857
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human BCAS1
          About Target
          Gene symbol: BCAS1
          Synonyms: AIBC1 NABC1
          Species: HUMAN
          Gene ID: 8537
          Summary: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_003657:4:3 NM_001366295:4:3 NM_001366296:4:3 NM_001366297:4:3 NM_001366298:4:3 NM_001316361:4:3 NM_001323347:4:3
      • Properties
        • * For Research Use Only.

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