Lentiviral human BAIAP2 sgRNA gene knockout kit

Human BAIAP2

Gene symbol: BAIAP2
Synonyms: BAP2 FLAF3 IRSP53
Species: HUMAN
Gene ID: 10458
Summary: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_017450:6:6 NM_017451:6:6 NM_001144888:6:6 NM_006340:6:6