Lentiviral human AXL sgRNA gene knockout kit

Human AXL

Gene symbol: AXL
Synonyms: ARK JTK11 Tyro7 UFO
Species: HUMAN
Gene ID: 558
Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_021913:8:8 NM_001699:8:8 NM_001278599:5:2