Lentiviral human ATP6V1H sgRNA gene knockout kit

Human ATP6V1H

Gene symbol: ATP6V1H
Synonyms: CGI-11 MSTP042 NBP1 SFD SFDalpha SFDbeta VMA13
Species: HUMAN
Gene ID: 51606
Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_015941:8:7 NM_213619:7:6 NM_213620:8:7