Lentiviral human APOBEC3B sgRNA gene knockout kit

Human APOBEC3B

Gene symbol: APOBEC3B
Synonyms: A3B APOBEC1L ARCD3 ARP4 bK150C2.2 DJ742C19.2 PHRBNL
Species: HUMAN
Gene ID: 9582
Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004900:2:2 NM_001270411:2:2