Lentiviral human AP1B1 sgRNA gene knockout kit

Lentiviral human AP1B1 sgRNA gene knockout kit

Catalog Number:
CGKK546825FEN
Mfr. No.:
HKO-610485
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human AP1B1
          About Target
          Gene symbol: AP1B1
          Synonyms: ADTB1 AP105A BAM22 CLAPB2
          Species: HUMAN
          Gene ID: 162
          Summary: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001127:5:4 NM_145730:5:4 NM_001166019:5:4
      • Properties
        • * For Research Use Only.

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