Lentiviral human ANKHD1 sgRNA gene knockout kit

Human ANKHD1

Gene symbol: ANKHD1
Synonyms: MASK MASK1 PP2500 VBARP
Species: HUMAN
Gene ID: 54882
Summary: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_017747:1:1 NM_017978:1:1 NM_024668:1:1 NM_001197030:1:1