Lentiviral human ANGPTL4 sgRNA gene knockout kit

Human ANGPTL4

Gene symbol: ANGPTL4
Synonyms: ARP4 FIAF HARP HFARP NL2 PGAR pp1158 TGQTL UNQ171
Species: HUMAN
Gene ID: 51129
Summary: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_139314:3:3 NM_001039667:3:3