Lentiviral human ADRA1A sgRNA gene knockout kit

Human ADRA1A

Gene symbol: ADRA1A
Synonyms: ADRA1C ADRA1L1 ALPHA1AAR
Species: HUMAN
Gene ID: 148
Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000680:2:1 NM_033303:1:1 NM_033302:1:1 NM_033304:1:1 NM_001322502:1:1 NM_001322503:1:1 NM_001322504:1:1