Lentiviral human ADCY5 sgRNA gene knockout kit

Human ADCY5

Gene symbol: ADCY5
Synonyms: AC5 FDFM
Species: HUMAN
Gene ID: 111
Summary: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_183357:5:5 NM_001199642:5:5