Lentiviral human ADAMTS7 sgRNA gene knockout kit

Human ADAMTS7

Gene symbol: ADAMTS7
Synonyms: ADAM-TS 7 ADAM-TS7 ADAMTS-7
Species: HUMAN
Gene ID: 11173
Summary: The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_014272:8:8