Lentiviral human ACTR1B sgRNA gene knockout kit

Human ACTR1B

Gene symbol: ACTR1B
Synonyms: ARP1B CTRN2 PC3
Species: HUMAN
Gene ID: 10120
Summary: This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_005735:6:6