Lentiviral human A1CF sgRNA gene knockout kit

Human A1CF

Gene symbol: A1CF
Synonyms: ACF ACF64 ACF65 APOBEC1CF ASP
Species: HUMAN
Gene ID: 29974
Summary: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_014576:9:7 NM_138932:9:7 NM_138933:9:7 NM_001198818:10:7 NM_001198819:11:7 NM_001198820:10:7 NM_001370130:8:7 NM_001370131:8:7