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Lenalidomide-OH

Lenalidomide-OH

Catalog Number:
L002441427INV
Mfr. No.:
V40200
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      • Overview

        • Lenalidomide-OH, a hydroxylated analog of Lenalidomide which is a cereblon (CRBN) ligand used for
          E3 ubiquitin ligase, can be used as a E3 ligase ligand in PROTACs for the recruitment of CRBN protein. Specifically, Lenalidomide-OH can be connected via a linker to the warhead in PROTACs that target a protein for degradation. Lenalidomide (also known as Revlimid,
          CC-5013) is a derivative of thalidomide approved in the United States
          in 2005 for the treatment for myeloma and blood disorders called
          myelodysplastic syndromes.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Ligands for E3 Ligase
          CAS Number
          1416990-08-3
          Molecular Formula
          C₁₃H₁₂N₂O₄
          Molecular Weight
          260.25
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          O=C1C2C=CC(=CC=2CN1C1C(NC(CC1)=O)=O)O

          * For research use only

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