LDHA Polyclonal Antibody (1 mg/mL) for WB, IHC

LDHA Polyclonal Antibody (1 mg/mL) for WB, IHC

Catalog Number:
A001511843RED
Mfr. No.:
RD90692A
Price:
$326
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      • Overview
        • Calculated MW: 23kDa
          Observed MW: 25kDa

          Please contact us at for specific academic pricing.

          Background

          LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant Human LDHA protein expressed by E.coli
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, l7R2, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19 (UniProt:P00338)

          * For reference only.

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:2500-1:5000
          IHC 1:200-1:400

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