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LC3-mHTT-IN-AN1

LC3-mHTT-IN-AN1

Catalog Number:
L002441404INV
Mfr. No.:
V2232
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      • Overview

        • LC3-mHTT-IN-AN1 (Compound AN1) is a novel mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduced mHTT levels in an allele-selective manner, and rescued disease-relevant phenotypes in cells and in vivo in fly and mouse models of Huntington's disease

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      • Properties
        • Categories
          ATTECs
          CAS Number
          486443-73-6
          Molecular Formula
          C15H9BR2NO3
          Molecular Weight
          411.05
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          BrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O

          * For research use only

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