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Overview
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L-Lactate is the major stereo-isomer of lactate formed in human intermediary metabolism and is present in blood. Depending on the level of exercise, blood levels of lactate can vary between 1 and 20 mM. Lactate is generated by lactate dehydrogenase (LDH) under hypoxic or anaerobic conditions. Monitoring lactate level is a good indicator of the balance between tissue oxygen demand and utilization. L-Lactate accumulates in lactic acidosis which is associated with poor prognosis and increased mortality in patients with critical illness, sepsis and liver failure.
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Overview