L-Glutathione Reduced

- Overview
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    Background
    
    L-Glutathione Reduced is an endogenous antioxidant, with the ability to scavenge oxygen-derived free radicals. L-Glutathione Reduced is a non-protein thiol widely present in living cells, which plays an important role in a series of biological events, including protein and DNA synthesis, enzyme activity, metabolism as well as cell protection. Not only does L-Glutathione Reduced scavenge oxygen-derived free radicals which contribute to the development of many common diseases including cancer, heart attack, stroke, arthritis, but it also helps in regenerating other antioxidants such as vitamin E and ascorbic acid. Thus, L-Glutathione Reduced is established to be a marker of oxidative stress. In addition, L-Glutathione Reduced is used for eluting glutathione S-transferase (GST) from glutathione agarose.
    
    Reference:
    1. Pereira-Rodrigues N, Cofré R, Zagal JH, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry, 2007, 70(1): 147-154.
- Properties
  - Categories
    
    An endogenous antioxidant
    
    Alternative Name
    
    (S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
    
    CAS Number
    
    70-18-8
    
    Molecular Formula
    
    C10H17N3O6S
    
    Molecular Weight
    
    307.32
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in EtOH; insoluble in DMSO; ≥14.25 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    SC[[email protected]@H](C(NCC(O)=O)=O)NC(CC[[email protected]@H](C(O)=O)N)=O
    
    * For Research Use Only