L-Arginine (hydrochloride)

L-Arginine (hydrochloride)

Catalog Number:
FC01366602APE
Mfr. No.:
APE-C6436
Price:
$156
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      • Overview
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          Background

          L-Arginine (hydrochloride) is the biological precursor of NO which serves as an important signal and effector molecule in animals. L-Arginine is a substrate for NO synthase which catalyzes the oxidation of L-arginine to NO and L-citrulline. NO released by vascular endothelial cells results in relaxation of strips of vascular tissue, as well as inhibition of platelet aggregation and platelet adhesion. L-arginine can be utilized by vascular endothelial cells for NO synthesis, and thereby serves as a potent vasodilator.

          1. Stuehr DJ. Enzymes of the L-arginine to nitric oxide pathway. Journal of Nutrition, 2004, 134(10 Suppl): 2748S-2751S.
          2. Palmer RM, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature, 1988, 333(6174): 664-666.
          3. Morikawa E, Moskowitz MA, Huang Z, et al. L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat. Stroke, 1994, 25(2): 429-435.

      • Properties
        • Categories
          A nitrogen donor for synthesis of nitric oxide (NO); a potent vasodilator
          Alternative Name
          (S)-(+)-Arginine hydrochloride; (S)-2-amino-5-guanidinopentanoic acid hydrochloride
          CAS Number
          1119-34-2
          Molecular Formula
          C6H15ClN4O2
          Molecular Weight
          210.66
          Purity
          98.00%
          Solubility
          insoluble in EtOH; insoluble in DMSO; ≥72.8 mg/mL in H2O
          Storage
          Store at -20°C
          SMILES
          NC(NCCC[[email protected]](N)C(O)=O)=N.Cl

          * For Research Use Only

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