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Kisspeptin 234

Kisspeptin 234

Catalog Number:
L002371049APE
Mfr. No.:
APE-B5489
Price:
$421
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

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          Background

          Kisspeptin 234 is a kisspeptin receptor antagonist, with the ability to antagonize kisspeptin-10-induced activation of gpr-54. Kisspeptin binds to its cognate receptor (i.e. gpr-54) on neurons that produce gonadotropin-releasing hormone (GnRH), and stimulates their activity, which in turn sends an obligatory signal for GnRH secretion, thereby gating down-stream events supporting reproduction. The development of kisspeptin receptor antagonists may provide a valuable tool for exploring the physiological and pathophysiological roles of kisspeptin in the regulation of reproduction, and could serve as a potential therapeutic agent for treating hormone-dependent disorders of reproduction, such as precocious puberty, endometriosis, as well as metastatic prostate cancer.

      • Properties
        • Categories
          A kisspeptin receptor antagonist
          Alternative Name
          (S,Z)-N'1-((6S,7Z,9R,10Z,13Z,15S,16Z,19Z,21S,22Z,24S)-9-((1H-indol-3-yl)methyl)-1-amino-15-benzyl-8,11,14,17,20,23-hexahydroxy-6-((Z)-hydroxy(((S)-1-hydroxy-1-imino-3-phenylpropan-2-yl)imino)methyl)-21-(2-hydroxy-2-iminoethyl)-1-imino-25-(1H-indol-3-yl)-2
          CAS Number
          1145998-81-7
          Molecular Formula
          C63H78N18O13
          Molecular Weight
          1295.42
          Appearance
          White lyophilised solid
          Purity
          98.00%
          Solubility
          insoluble in DMSO; insoluble in EtOH; ≥4.44 mg/mL in H2O with ultrasonic
          Storage
          Store at -20°C
          SMILES
          C[[email protected]](/N=C(O)/C)([H])/C(O)=N/[[email protected]@](/C(O)=N/[[email protected]@](/C(O)=N/[[email protected]@](/C(O)=N/C/C(O)=N/[[email protected]@](/C(O)=N/C/C(O)=N/[[email protected]](/C(O)=N/[[email protected]@](/C(O)=N/[[email protected]@](C(O)=N)([H])CC1=CC=CC=C1)([H])CCCNC(N)=N)([H])CC2=CNC3=CC=CC=C23)([H])CC4=CC=CC=C4)([H])CC(O)=N)([H])CC5=CNC6=CC=CC=C56

          * For Research Use Only

    Documents

    COA (Certificate Of Analysis)

    MSDS (Material Safety Data Sheet)

    Datasheet

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