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Overview
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Calculated MW: 21kDa/23kDa
Observed MW: Refer to figuresPlease contact us at for specific academic pricing.
Background
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
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