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Overview
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KAT2A Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 447 amino acids (411-837 a.a) and having a molecular mass of 51.1kDa. KAT2A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. General control of amino acid synthesis protein 5 like 2 (KAT2A) is a member of the GCN5 family. KAT2A functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. KAT2A interacts with Ku70, TAF9, transcription initiation protein SPT3 homolog, TADA2L, Ku80 and DDB1.
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Overview