Name: ITM2B Polyclonal Antibody (1.2 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 30 kDa
  Observed MW: Refer to figures
  Gene Accession: BC000554
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Fusion protein of human ITM2B
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.2 mg/mL
  
  Antigen
  
  ABRI, ABri/ADan amyloid peptide, BRI 2, BRI, BRI2, BRICD 2B, BRICD2B, BRICHOS domain containing 2B, E25B, E3 16, E3-16, FBD, imBRI2, Immature BRI2, Integral membrane protein 2B, ITM 2B, ITM2B, ITM2B, Protein E25B, RDGCA, Transmembrane protein BRI (UniProt:Q9Y287)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:30-1:150
ELISA	1:5000-1:10000

ITM2B Polyclonal Antibody (1.2 mg/mL) for WB, IHC, ELISA

ITM2B Polyclonal Antibody (1.2 mg/mL) for WB, IHC, ELISA

Background

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