ISCU Polyclonal Antibody (0.78 mg/mL) for IHC, ELISA

ISCU Polyclonal Antibody (0.78 mg/mL) for IHC, ELISA

Catalog Number:
A001508188RED
Mfr. No.:
RD252700A
Price:
$253
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      • Overview
        • Gene Accession: BC011906

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          Background

          This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human ISCU
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.78 mg/mL
          Antigen
          2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homolog, ISCU, ISU2, MGC74517, mitochondrial, NIFU, NifU like N terminal domain containing, NifU like N terminal domain containing protein, NifU like protein, NifU-like N-terminal domain-containing protein, NifU-like protein, NIFUN, Nitrogen fixation cluster like, OTTHUMP00000238760, OTTHUMP00000238761, OTTHUMP00000238762, OTTHUMP00000238764, OTTHUMP00000238765 (UniProt:Q9H1K1)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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