IRS-1(Phospho-Ser312) Antibody

IRS-1(Phospho-Ser312) Antibody

Catalog Number:
A001548023RED
Mfr. No.:
RDSA62141
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Peptide sequence around phosphorylation site of serine 312 (A-T-S(p)-P-A) derived from Human IRS-1.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Antigen
          HIRS-1;IRS1;Insulin receptor substrate 1 (Gene ID:3667; UniProt:P35568)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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