IL6ST Polyclonal Antibody (0.7 mg/mL) for IHC, ELISA

IL6ST Polyclonal Antibody (0.7 mg/mL) for IHC, ELISA

Catalog Number:
A001508046RED
Mfr. No.:
RD252510A
Price:
$253
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      • Overview
        • Gene Accession: BC117402

          Please contact us at for specific academic pricing.

          Background

          The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human IL6ST
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.7 mg/mL
          Antigen
          CD130, CD130 antigen, CDw130, gp130, GP130 RAPS, IL 6R beta, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, IL6 ST, IL6RB, IL6ST, Interleukin 6 receptor subunit beta, Interleukin receptor beta chain, Interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, Membrane glycoprotein gp130, Oncostatin M receptor, Oncostatin M receptor alpha subunit, Oncostatin-M receptor subunit alpha (UniProt:P40189)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:30-1:150
          ELISA 1:5000-1:10000

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