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Overview
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Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation, differentiation and specific functions of many cell types. IGF-II is identical with Somatomedin C (Sm-C) and has a molecular weight of 7469 daltons. Its major regulators are growth hormone (GH) and nutrition, although its production in specific tissues is affected by a multitude of tropic hormones and other peptide growth factors. In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP).
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- Properties
- Applications
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Overview