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HUWE1 Polyclonal Antibody

HUWE1 Polyclonal Antibody

Catalog Number:
A001507387RED
Mfr. No.:
RD219540A
Price:
$253
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      • Overview

        • Gene Accession: NP113584

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide of human HUWE1
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.8 mg/mL
          Antigen
          ARF binding protein 1, ARF BP1, ARF-binding protein 1, ARF-BP1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT domain protein LASU1, HECT UBA and WWE domain containing protein 1, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, Huwe1, HUWE1, Ib772, Large structure of UREB1, LASU1, Mcl 1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, Mule, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, URE-B1, URE-binding protein 1, UREB1 (UniProt:Q7Z6Z7)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:10-1:50
          ELISA 1:5000-1:10000

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