Name: HUS1 Recombinant Protein
Price: Inquiry

- Overview
  - HUS1 produced in E. Coli is a single, non-glycosylated polypeptide chain containing 300 amino acids (1-280a.a.) and having a molecular mass of 33.8kDa. HUS1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. HUS1 protein connects with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, that confines to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    HUS1 Checkpoint Homolog (S. pombe), Checkpoint Protein HUS1, Hus1+-like protein.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95% as determined by SDS-PAGE.
    
    Formulation
    
    The HUS1 protein solution (0.25mg/1ml) is formulated in . In 20 mM Tris-HCl Buffer (pH 8.0), 100 mM NaCl and 40% Glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

HUS1 Recombinant Protein

HUS1 Recombinant Protein

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