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Target Information
Target NameVery Low-Density Lipoprotein Receptor; Vldl Receptor; Vldl-RDatabase LinksVLDLR_HUMAN ; Reactome: R-HSA-8866376 ; Gene ID: 7436About TargetTissue Specificity: Abundant in heart and skeletal muscle.also ovary and kidney.not in liver.
Function: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
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