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Overview
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This VEGFA ELISA kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Please contact us at for specific academic pricing.
Target Information
Target NameVascular Endothelial Growth Factor A; Vegf-A; Vascular Permeability Factor; VpfDatabase LinksUniprot ID: TRFR_HUMAN ; Reactome: R-HSA-114608 ; Gene ID: 7422 ; Gene Symbol: VEGFAAbout TargetFunction: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
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