Name: Human Transforming Growth Factor-beta 1
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- Overview
  - Dimer, 12.8/25.6 kDa (112/224 aa). Transforming growth factor-beta 1 (TGF-b1) is a member of the TGF-beta superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-b1 signals through SMAD proteins via the TGF-bRI and TGF-bRII receptors.
    
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- Properties
  - Protein Name
    
    Transforming growth factor beta-1, TGF-beta-1
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1 % trifluoroacetic acid (TFA) and Trehalose in a 20:1 Trehalose to protein ratio
    Sterile 10 mM HCl at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Inhibition of IL-4-induced HT-2 cell proliferation at = 2.0 x 10^6 units/mg. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    P01137
    
    Gene ID
    
    7040
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Transforming Growth Factor-beta 1

Human Transforming Growth Factor-beta 1

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