Human Stromal Cell-Derived Factor-1 beta (CXCL12)

Human Stromal Cell-Derived Factor-1 beta (CXCL12)

Catalog Number:
P001418355ABE
Mfr. No.:
Abe32-12308
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      • Overview
        • Predicted MW: Monomer, 8.5 kDa (72 aa). Stromal cell-derived factor-1 beta (SDF-1 beta ), also called CXCL12b, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1 beta signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes.

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      • Properties
        • Protein Name
          Stromal cell-derived factor 1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, Pre-B cell growth-stimulating facto
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          6387

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

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