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Overview
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Human SDF-1beta Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
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Background
SDF-1? and ? are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1? and ? chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1? and ? contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1? protein, produced by an N-terminal truncation of two additional amino acids, after removal of the signal sequence, contains 72 amino acid residues. Recombinant Human SDF-1? is an 8.5 kDa protein containing 72 amino acid residues.
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- Properties
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Overview